Cancer Genomics & Proteomics

Cancer Genomics & Proteomics is an international, bimonthly journal devoted to the publication of original high quality articles and reviews on the applications of genomic and proteomic technology to basic, experimental, and clinical cancer research.

List Price: $ 577.80

Price: $ 577.80

Lance Armstrong and David Agus at TEDMED2011


Image by Klick Pharma
Lance and David in conversation at TEDMED2011.

LANCE ARMSTRONG
Chairman & Founder, The Lance Armstrong Foundation

One of the world’s best cyclists by the age of 25, Lance Armstrong’s competitive nature helped him confront late stage testicular cancer that had spread to his abdomen, lungs and brain. In 1997, he established the Lance Armstrong Foundation, now known by its powerful brand – LIVESTRONG® – to serve people and families affected by cancer. He returned to cycling and became the record-holding seven-time winner of the Tour de France.

A leading advocate for cancer survivors, Lance was appointed to serve on the President’s Cancer Panel, an advisory group that reports directly to the President, and represented cancer survivors worldwide at the United Nations this September.

Under Lance’s leadership, LIVESTRONG has raised more than 0 million for survivor services and advocacy and was instrumental in the passage of Proposition 15 in Texas, an initiative that allocated billion for the fight against cancer and created the Cancer Prevention and Research Institute of Texas.

Lance is a father of five and splits his time between Austin and Aspen.

DAVID AGUS
PROFESSOR OF MEDICINE, UNIVERSITY OF SOUTHERN CALIFORNIA

David B. Agus is a Professor of Medicine and Engineering at the USC Keck School of Medicine and Viterbi School of Engineering and heads USC’s Westside Cancer Center and the Center for Applied Molecular Medicine. His research focuses on the application of proteomics and genomics for the study of disease and the development of new therapeutics for cancer. Dr. Agus is an international leader in new technologies and approaches for personalized healthcare. Dr. Agus received various honors and awards, including the 2009 GQ Magazine Rockstar of Science Award. He is the founder of Oncology.com, the largest cancer internet resource/community, Applied Proteomics, and of Navigenics, a genomic health care technology and wellness company. Dr. Agus’ book called “The End of Illness” is due out in December from the Free Press division of Simon and Schuster.

Question by : Creationists, where do you stand on this..?
Researchers from Cambridge, Glasgow and Greece have discovered a remarkable amount of plasticity in how transcription factors, the proteins that bind to DNA to control the activation of genes, maintain their function over large evolutionary distances.

Reporting in the journal Science, the authors traced the evolution of gene regulation by comparing the binding of evolutionarily conserved transcription factors in the genomes of five vertebrate species — human, dog, mouse, short-tailed opossum and chicken — spanning 300 million years

Paul Flicek, leader of the Vertebrate Genomics Team at EMBL-EBI, an outstation of the European Molecular Biology Laboratory, and coauthor on the paper said “The evolutionary changes in transcription factor binding in the five species have left clues that we can use to explain how function is preserved but not necessarily sequence. What we have learnt is that although the transcription factors regulate similar target genes in all five species, the binding events underpinning this regulation have not been conserved as the species diverged.”

“By studying changes in transcription factor binding, we can understand the evolution of gene regulation,” said Duncan Odom from Cancer Research UK Cambridge Research Institute and coauthor on the paper. He continued: “Differences in gene regulation are central to explaining differences between species, and gene misregulation is a key causative factor in diseases like cancer.”

The results reveal that sequence conservation is not the whole story when it comes to maintaining tissue-specific gene regulation.

What’s your position on these findings..?

Thank you

Best answer:

Answer by So-Crates Resurrected AGAIN
Creationist: “300 Million years? Pshaw – everyone knows the earth is only 6000 years old, so this isnt possible at all…”

Give your answer to this question below!